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Created on: 24-Nov-2012   Last updated on: 14-Feb-2014  |  How to cite this?
Total resources - 69
A list of resources for pharmacokinetics and pharmacodynamics
Akhil Patel and Anu KC (Correspondence: Acharya KK, kshitish@ibab.ac.in)

Resources
Short description*Rank by usage frequency Click to Edit / Add comments
RC - Resource Clinical
http://www.resourceclinical.com/
It is an online resource portal directory containing clinical pharmacy, clinical medicine and drug information links for the busy physician, pharmacist and other healthcare professionals.
1
KINETICS©
http://www.rxkinetics.com/kinetics.html
A database mainly designed by and for the practicing pharmacist and provides an easy to use pk dosing tool for adult patients.
28
Drugbank
http://www.drugbank.ca/
It is a unique bioinformatics and cheminformatics resource that combines detailed drug (i.e. chemical, pharmacological and pharmaceutical) data with comprehensive drug target (i.e. sequence, structure, and pathway) information.
50
bear
http://pkpd.kmu.edu.tw/bear/
The data analysis tool for Average BioEquivalence (ABE) and BioAvailability (BA) for user.
65
Clinical pharmacology
http://www.clinicalpharmacology-ip.com/Forms/login.aspx?ReturnUrl=%2fdefault.aspx
It is a full database that covers drugs, investigational drugs, herbal products, nutraceuticals and nutritional products.
80
SIDER 2 - Side Effect Resource
http://sideeffects.embl.de/
Provides information about side effect frequency, drug and side effect classifications as well as links to further information.
86
Berkeley Madonna
http://www.berkeleymadonna.com/
A database, which helps in constructing mathematical models for research and teaching.
96
IUPHAR - The International Union of Basic and Clinical Pharmacology Database
http://www.iuphar-db.org/
Database of the IUPHAR Committee on receptor nomenclature and drug classification.
96
PROMISCUOUS
http://bioinformatics.charite.de/promiscuous/
It is an exhaustive resource of protein-protein and drug-protein interactions, which aims to provide a uniform data-set for drug repositioning and its analysis and it contains three entities: proteins and side-effects as well as relations between them.
96
DART - Drug Adverse Reaction Target
http://bidd.nus.edu.sg/group/drt/dart.asp
A database, which contains information about known drug adverse rection targets, functions and properties.
97
APIS
http://www.miips.fr/Cadre_produit_1.htm
It helps in model identification, stimulation and dosage regimen calculations in clinical and experimental pharmacokinetics.
98
BIOSOFT
http://www.biosoft.com/
A windows based scientific software package for a wide range of purposes like- data analysis, graph plotting, statistics, densitometry, dose-effect analysis, assays, curve-fitting, enzyme kinetics, teaching and more.
98
IDIS - Integrated Disbursement & Information System
http://itsnt14.its.uiowa.edu/
A database, which is developed to retrieve specific information about a drug and/or drug treatment of a disease state.
98
ADME - Absorption, Distribution, Metabolism, Excretion database (by aureus sciences)
http://www.aureus-sciences.com/aureus/web/guest/adme-overview
A database associated with known Absorption, Distribution, Metabolism, Excretion (ADME) properties, including human oral bioavailability, enzymes metabolism, inhibition and induction, transport, plasma protein binding and blood-brain barrier.
99
ADME - Absorption, Distribution, Metabolism, Excretion databases (by UCSD)
http://modem.ucsd.edu/adme/databases/databases.htm
A database with six different databases, collected from literature related to drug discovery, Absorption, Distribution, Metabolism, Excretion (ADME) including water solubility (logS) datatabase, Caco-2 permeability database, blood-brain permeability database, P-gp inhibitor database, oral absorption database, oral bioavailability database and combined databases.
99
Boomer
http://www.boomer.org/
Non-linear regression database for the analysis of pharmacokinetic and pharmacodynamic data.
99
CalcuSyn
http://www.biosoft.com/w/calcusyn.htm
It is an analyzer of combined drug effects, and enables automatic quantification of phenomena like synergism and inhibition during mixed drug treatments.
99
acslXtreme
http://www.acslsim.com/
It helps in modeling, execution, and analysis environment for continuous dynamic systems and processes.
100
ADME-AP - Absorption, Distribution, Metabolism, Excretion -Associated Protein
http://bidd.nus.edu.sg/group/admeap/admeap.asp
It contains information about known drug Absorption, Distribution, Metabolism, Excretion (ADME) associated proteins, functions, similarities, substrates / ligands, tissue distributions, and other properties of the targets.
100
ADMEDB by FUJITSU
http://www.fqs.pl/chemistry_materials_life_science/products/adme_db
It is mainly designed for use in drug research and development, including drug-drug interactions and ADME (Absorption, Distribution, Metabolism and Excretion) studies that contain the latest and most comprehensive data on interactions of substances with drug metabolizing enzymes and drug transporters.
100
admetSAR
http://www.admetexp.org/
It is helpful for in silico screening Absorption, Distribution, Metabolism, Excretion and Toxicity (ADMET) profiles of drug candidates and environmental chemicals.
100
Antibiotic Kinetics©
http://www.rxkinetics.com/abpk.html
It is a pharmacokinetics program without any patient database features and is currently being used at over 3000 sites worldwide.
100
Anti-cancer agent mechanism database
http://dtp.nci.nih.gov/docs/cancer/searches/standard_mechanism.html
A database, which contains a set of 122 compounds with anti-cancer activity and reasonably well known mechanism of action.
100
APK© - Adult and Pediatric Kinetics
http://www.rxkinetics.com/apk.html
It is a pharmacokinetics program, which provides essential information to serve the practicing pharmacist.
100
Bioeqv52, Biopar40 and Bioeqnew
http://www.sciencedirect.com/science/article/pii/0169260794901007
 A software that performs bioequivalence calculations including statistical power.
100
Biokmod
http://web.usal.es/~guillermo/biokmod.htm
A mathematica toolbox for solving system of differential equations and for fitting coefficients with application for modeling Biokinetic systems and also includes the current International Commission on Radiological Protection (ICRP) biokinetic models, which can be applied in pharmacokinetic, internal dosimetry, bioassay evaluations, nuclear medicine and more.
100
Biokmod web
http://www3.enusa.es/webMathematica/Public/biokmod.html
A program developed in Mathematica, web Mathematica and Java. It runs online and can be applied in pharmacokinetic, internal dosimetry and nuclear medicine.
100
BIOPAK
http://andrewsforest.oregonstate.edu/data/tools/software/biopak.cfm?topnav=149
It is a menu-driven package of computer programs for personal computers that calculates the biomass, area, height, length, or volume of plant components (leaves, branches, stem, crown, and roots) and biomass by fuels size classes using existing prediction equations.
100
Biotrial
http://www.biotrial.com/
It provides high-quality pharmacology services.
100
Celerion
http://celerion.com/service/pharmacokineticspharmacodynamics-pkpd
A database, which includes PK and PD analysis and parameter calculation, study design input, written interpretation of PK and PD results for ICH study reports & consultation on PK/PD topics.
100
CEPKPD - Center of Excellence in Pharmacokinetics and Pharmacodynamics
http://pharmsci.buffalo.edu/CEPKPD/index.shtml
A database by University at Buffalo-SUNY(UB) to promote the development and application of PK/PD to the problems and challenges of drug therapy.
100
CHIME - Centre for Health Informatics & Multiprofessional Education
http://www.ucl.ac.uk/chime/
Database that support clinical practice and benefits the communities - both patients and health care professionals - locally, nationally and globally.
100
Cloe Gateway
https://www.cloegateway.com/services/cloe_knowledge/pages/search.php
A leading provider of Absorption, Distribution, Metabolism, Excretion (ADME) screening and prediction services to the Pharmaceutical and Biotech industry.
100
CXT
http://www.boomer.org/pkin/cxt.html
It is a program for analysis of linear dynamic systems in the frequency domain.
100

URL not working as on 15 Nov 2016 (confirmed on 23 Feb 2017)
Cyber PatientTM
http://www.labsoft.com/www/software.html
A windows based multimedia PharmacoKinetic (PK) simulation program.
100
Duck flats pharma database
http://www.dfpharma.com/
It helps to set up and implement a strategic development plan focusing on the mechanism of action, efficacy and pharmacokinetics of the drug or biotechnology compound being developed.
100
Gold standard drug database
http://www.goldstandard.com/product/gold-standard-drug-database/
 An extensive and integrated drug database, which assists in taking intelligent drug decisions in every healthcare setting.
100
ICPD - Institute for Clinical PharmacoDynamics
http://www.icpd.com/
Assists pharmaceutical and biotechnology companies to provide safer and more effective drugs to patients through advanced methods of pharmacokinetic and pharmacodynamic system analysis.
100
Intellipharm PK
http://www.pharmaceuticalonline.com/doc/intellipharm-pk-0001
It is mainly developed for windows that simulates drug plasma concentrations based on drug's physical and pharmacokinetic parameters.
100
ivivc for R
http://pkpd.kmu.edu.tw/ivivc/
A tool for in vitro-in vivo correlation.
100
JGuiB
http://pkpd.kmu.edu.tw/jguib/
A computer program that includes PK/PD modeling: normal fitting, stimulation and Bayesian estimation that is written in java work with boomer.
100
JPKD - JavaPK for Desktop
http://pkpd.kmu.edu.tw/jpkd/
It is a Clinical PharmacoKinetic (CPK) service (or Therapeutic Drug Monitoring (TDM)) computer program for desktop.
100
MacDope
http://openagricola.nal.usda.gov/Record/CAT88907258
A computer program by National Agricultural Library (NAL) mainly for Pharmacology, Pharmacokinetics, drugs and metabolism.
100
MedRoc
http://www.stenstat.com/
It is an integrated solution for performing ROC analyses of medical data.
100
mobilePK
http://pkpd.kmu.edu.tw/mobilepk/
A computer program designed for Clinical PharmacoKinetic (CPK) services (or Therapeutic Drug Monitoring, TDM)) running on Android mobile phone.
100
NCI DIS 3D Database - The National Cancer Institute 3D Structure Database
http://dtp.nci.nih.gov/docs/3d_database/dis3d.html
It is a collection of 3D structures for over 400,000 drugs, which was built and is maintained by the developmental therapuetics program division of cancer treatment, national cancer institute.
100
PDx-IVIVC
http://www.iconplc.com/services/preclinical-phase-i/
Provides information on the early-phase in clinical research, bioanalytical, PK/PD modeling & simulation.
100
PharmacoDynamics (PD) Plus
www.simulations-plus.com
Automated model selection that adds the pharmacodynamics table, which contains the PD model, the site of PD action, and the parameters that determine the kinetics of the action.
100
Phish Pharm
http://www.accessdata.fda.gov/scripts/SDA/sdNavigation.cfm?sd=PhishPharm
A searchable database of pharmacokinetics data in fish.
100
PHYSPROP - The physical properties database
http://www.srcinc.com/what-we-do/environmental/scientific-databases.html
A database, which contains chemical structures, names and physical properties for over 41,000 chemicals.
100
PK Solutions
http://www.summitpk.com/pksolutions/pksolutions.htm
It is an automated excel-based program that does single and multiple dose pharmacokinetic data analysis of concentration-time data from biological samples (blood, serum, plasma, lymph, etc.) following intravenous or extravascular routes of administration.
100
PK/DB - DataBase for PharmacoKinetic properties
http://miro.ifsc.usp.br/pkdb/
A freely available database for pharmacokinetic properties and predictive in silico Absorption, Distribution, Metabolism, Excretion (ADME) models.
100
PKfit for R
http://cran.csie.ntu.edu.tw/web/packages/PKfit/index.html
It is an R package nonlinear regression (including a genetic algorithm) program, which was designed to perform model/curve fitting and model simulations for pharmacokinetics.
100
PK-Sim
http://www.systems-biology.com/products/pk-sim.html
A software tool for whole-body physiologically based pharmacokinetic modeling.
100
PROPKA
http://en.wikipedia.org/wiki/Protein_pKa_calculations
PROPKA is a heuristic pKa calculation software package developed by Jan Jensen at University of Copenhagen.
100
PubPk - the pK database
http://www.pubpk.org/index.php?title=Main_Page
A free online database for pharmacokinetics and phamacodynamics data including some articles.
100
RxMED
http://www.rxmed.com/
A database, which contains documented, authoritative and detailed information on over 3000 prescription pharmaceuticals that also includes general pharmacology, indications, warnings, dosage and adverse effects information for each pharmaceutical monograph.
100
SAAM30 and CONSAM
http://septentrio.uit.no/index.php/rangifer/article/viewFile/819/785
Computer programs for performing non- linear regression analysis.
100
tdm for R
http://pkpd.kmu.edu.tw/tdm/
An R package for therapeutic drug monitoring.
100
TPNassist©
http://www.rxkinetics.com/tpn.html
A clinical tool mainly developed for pharmaceutical care, which combines comprehensive database functions and nutritional assessment into a single user-friendly package.
100
Transparency market research (Computational Biology )
http://www.transparencymarketresearch.com/computational-biology.html
It contains the information about pharmacodynamics, cellular modeling, computational genomics, proteomics, pharmacogenomics, pharmacokinetics, human simulation software, drug discovery & development.
100
TTD - Therapeutic Target Database
http://bidd.nus.edu.sg/group/ttd/ttd.asp
Therapeutic database, which contains information about target function, sequence, 3D structure, ligand binding properties, enzyme nomenclature and drug structure, therapeutic class, clinical development status.
100
UKMi - UK Medicines Information
http://www.ukmi.nhs.uk/ukmi/about/default.asp?pageRef=1
A National Health Service (NHS) pharmacy based service, which aims to support the safe, effective and efficient use of medicines by the provision of evidence-based information and advice on their therapeutic use.
100
University of Washington pharmacokinetics laboratory
http://sop.washington.edu/pklab
A database that support both preclinical and clinical research protocols through the development and utilization of bioanalytical methods.
100
WinSAAM
http://www.winsaam.com/
Windows oriented modeling program enabling the user to explore biological systems using mathematical models.
100
WOMBAT PK
http://www.sunsetmolecular.com/index.php?option=com_content&view=article&id=16&Itemid=11
It contains clinical pharmacokinetic measurements; it further includes physico-chemical properties; toxicity endpoints, and annotated drug-target bioactivities.
100
Mathworks
http://www.mathworks.in/discovery/pharmacokinetic.html
A pharmacokinetics software tool for entire PharmacoKinetic and PharmacoDynamic workflow, from modeling to analysis, within a single graphical environment.
100
NONMEM® 
http://www.iconplc.com/technology/products/nonmem/
It is an ICON's nonlinear mixed effects modelling tool. It is used in population pharmacokinetic and pharmacodynamic analysis and it was developed by University of California.
100
ADAPT II 
http://legacy.samsi.info/201011/pkpd/SoftwareDZD.pdf
A computational tool for PK/PD modeling. It is also used PK/PD data analysis applications.
100
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